Development and characterisation of a novel glucagon like peptide-1 receptor antibody

AIMS/HYPOTHESIS: Glucagon like peptide-1 (GLP-1) enhances glucose-dependent insulin secretion by binding to GLP-1 receptors (GLP1Rs) on pancreatic beta cells. GLP-1 mimetics are used in the clinic for the treatment of type 2 diabetes, but despite their therapeutic success, several clinical effects o...

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Detalles Bibliográficos
Autores principales: Biggs, Emma K., Liang, Lihuan, Naylor, Jacqueline, Madalli, Shimona, Collier, Rachel, Coghlan, Matthew P., Baker, David J., Hornigold, David C., Ravn, Peter, Reimann, Frank, Gribble, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890879/
https://www.ncbi.nlm.nih.gov/pubmed/29119245
http://dx.doi.org/10.1007/s00125-017-4491-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890879/
https://www.ncbi.nlm.nih.gov/pubmed/29119245
http://dx.doi.org/10.1007/s00125-017-4491-0

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