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Effects of mechanical stretching on the morphology of extracellular polymers and the mRNA expression of collagens and small leucine-rich repeat proteoglycans in vaginal fibroblasts from women with pelvic organ prolapse

To determine the effect of mechanical stretching load and the efficacy of postmenopausal estrogen therapy (ET) on pelvic organ prolapse (POP), vaginal fibroblasts isolated from postmenopausal women with or without POP were subjected to 0.1-Hz uniaxial cyclic mechanical stretching (CS) with 10% elong...

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Detalles Bibliográficos
Autores principales: Wang, Sumei, Lü, Dongyuan, Zhang, Zhenyu, Jia, Xingyuan, Yang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890965/
https://www.ncbi.nlm.nih.gov/pubmed/29630675
http://dx.doi.org/10.1371/journal.pone.0193456

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