Glial loss of the metallo β-lactamase domain containing protein, SWIP-10, induces age- and glutamate-signaling dependent, dopamine neuron degeneration

Across phylogeny, glutamate (Glu) signaling plays a critical role in regulating neural excitability, thus supporting many complex behaviors. Perturbed synaptic and extrasynaptic Glu homeostasis in the human brain has been implicated in multiple neuropsychiatric and neurodegenerative disorders includ...

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Detalles Bibliográficos
Autores principales: Gibson, Chelsea L., Balbona, Joseph T., Niedzwiecki, Ashlin, Rodriguez, Peter, Nguyen, Ken C. Q., Hall, David H., Blakely, Randy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891035/
https://www.ncbi.nlm.nih.gov/pubmed/29590100
http://dx.doi.org/10.1371/journal.pgen.1007269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891035/
https://www.ncbi.nlm.nih.gov/pubmed/29590100
http://dx.doi.org/10.1371/journal.pgen.1007269

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