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Characterization of a novel OTX2‐driven stem cell program in Group 3 and Group 4 medulloblastoma

Medulloblastoma (MB) is the most common malignant primary pediatric brain cancer. Among the most aggressive subtypes, Group 3 and Group 4 originate from stem/progenitor cells, frequently metastasize, and often display the worst prognosis, yet we know the least about the molecular mechanisms driving...

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Detalles Bibliográficos
Autores principales: Stromecki, Margaret, Tatari, Nazanin, Morrison, Ludivine Coudière, Kaur, Ravinder, Zagozewski, Jamie, Palidwor, Gareth, Ramaswamy, Vijay, Skowron, Patryk, Wölfl, Matthias, Milde, Till, Del Bigio, Marc R., Taylor, Michael D., Werbowetski‐Ogilvie, Tamra E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891039/
https://www.ncbi.nlm.nih.gov/pubmed/29377567
http://dx.doi.org/10.1002/1878-0261.12177