STAT1 is a sex‐specific tumor suppressor in colitis‐associated colorectal cancer

The interferon‐inducible transcription factor STAT1 is a tumor suppressor in various malignancies. We investigated sex‐specific STAT1 functions in colitis and colitis‐associated colorectal cancer (CRC) using mice with specific STAT1 deletion in intestinal epithelial cells (STAT1(∆IEC)). Male but not...

Descripción completa

Detalles Bibliográficos
Autores principales: Crnčec, Ilija, Modak, Madhura, Gordziel, Claire, Svinka, Jasmin, Scharf, Irene, Moritsch, Stefan, Pathria, Paulina, Schlederer, Michaela, Kenner, Lukas, Timelthaler, Gerald, Müller, Mathias, Strobl, Birgit, Casanova, Emilio, Bayer, Editha, Mohr, Thomas, Stöckl, Johannes, Friedrich, Karlheinz, Eferl, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891040/
https://www.ncbi.nlm.nih.gov/pubmed/29419930
http://dx.doi.org/10.1002/1878-0261.12178

Ejemplares similares

Ejemplares similares