Novel function of HATs and HDACs in homologous recombination through acetylation of human RAD52 at double-strand break sites

The p300 and CBP histone acetyltransferases are recruited to DNA double-strand break (DSB) sites where they induce histone acetylation, thereby influencing the chromatin structure and DNA repair process. Whether p300/CBP at DSB sites also acetylate non-histone proteins, and how their acetylation aff...

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Detalles Bibliográficos
Autores principales: Yasuda, Takeshi, Kagawa, Wataru, Ogi, Tomoo, Kato, Takamitsu A., Suzuki, Takehiro, Dohmae, Naoshi, Takizawa, Kazuya, Nakazawa, Yuka, Genet, Matthew D., Saotome, Mika, Hama, Michio, Konishi, Teruaki, Nakajima, Nakako Izumi, Hazawa, Masaharu, Tomita, Masanori, Koike, Manabu, Noshiro, Katsuko, Tomiyama, Kenichi, Obara, Chizuka, Gotoh, Takaya, Ui, Ayako, Fujimori, Akira, Nakayama, Fumiaki, Hanaoka, Fumio, Sugasawa, Kaoru, Okayasu, Ryuichi, Jeggo, Penny A., Tajima, Katsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891081/
https://www.ncbi.nlm.nih.gov/pubmed/29590107
http://dx.doi.org/10.1371/journal.pgen.1007277

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