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Modulation of AKR1C2 by curcumin decreases testosterone production in prostate cancer

Intratumoral androgen biosynthesis has been recognized as an essential factor of castration‐resistant prostate cancer. The present study investigated the effects of curcumin on the inhibition of intracrine androgen synthesis in prostate cancer. Human prostate cancer cell lines, LNCaP and 22Rv1 cells...

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Detalles Bibliográficos
Autores principales: Ide, Hisamitsu, Lu, Yan, Noguchi, Takahiro, Muto, Satoru, Okada, Hiroshi, Kawato, Suguru, Horie, Shigeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891173/
https://www.ncbi.nlm.nih.gov/pubmed/29369461
http://dx.doi.org/10.1111/cas.13517