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IgA Vasculitis with Simultaneous Cardiopulmonary Involvement

A 60-year-old man with a history of hypertension, type 2 diabetes, and reflux esophagitis was admitted to our hospital with hemoptysis, dyspnea, and leg edema. We diagnosed him with adult IgA vasculitis based on the presence of purpura, elevated serum IgA fibronectin complexes, pathophysiological fi...

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Detalles Bibliográficos
Autores principales: Bando, Kazunori, Maeba, Hirofumi, Shiojima, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891522/
https://www.ncbi.nlm.nih.gov/pubmed/29225270
http://dx.doi.org/10.2169/internalmedicine.9681-17
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author Bando, Kazunori
Maeba, Hirofumi
Shiojima, Ichiro
author_facet Bando, Kazunori
Maeba, Hirofumi
Shiojima, Ichiro
author_sort Bando, Kazunori
collection PubMed
description A 60-year-old man with a history of hypertension, type 2 diabetes, and reflux esophagitis was admitted to our hospital with hemoptysis, dyspnea, and leg edema. We diagnosed him with adult IgA vasculitis based on the presence of purpura, elevated serum IgA fibronectin complexes, pathophysiological findings, a skin biopsy showing leukocytoclastic vasculitis, and immunofluorescence studies demonstrating granular IgA and C3 deposits in the blood vessel wall. He showed concurrent cardiopulmonary involvement without involvement of the gastrointestinal system and kidneys, which are commonly affected in IgA vasculitis patients. Following treatment with prednisolone, the patient recovered with improvement in cardiopulmonary manifestations.
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spelling pubmed-58915222018-04-12 IgA Vasculitis with Simultaneous Cardiopulmonary Involvement Bando, Kazunori Maeba, Hirofumi Shiojima, Ichiro Intern Med Case Report A 60-year-old man with a history of hypertension, type 2 diabetes, and reflux esophagitis was admitted to our hospital with hemoptysis, dyspnea, and leg edema. We diagnosed him with adult IgA vasculitis based on the presence of purpura, elevated serum IgA fibronectin complexes, pathophysiological findings, a skin biopsy showing leukocytoclastic vasculitis, and immunofluorescence studies demonstrating granular IgA and C3 deposits in the blood vessel wall. He showed concurrent cardiopulmonary involvement without involvement of the gastrointestinal system and kidneys, which are commonly affected in IgA vasculitis patients. Following treatment with prednisolone, the patient recovered with improvement in cardiopulmonary manifestations. The Japanese Society of Internal Medicine 2017-12-08 2018-03-15 /pmc/articles/PMC5891522/ /pubmed/29225270 http://dx.doi.org/10.2169/internalmedicine.9681-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Bando, Kazunori
Maeba, Hirofumi
Shiojima, Ichiro
IgA Vasculitis with Simultaneous Cardiopulmonary Involvement
title IgA Vasculitis with Simultaneous Cardiopulmonary Involvement
title_full IgA Vasculitis with Simultaneous Cardiopulmonary Involvement
title_fullStr IgA Vasculitis with Simultaneous Cardiopulmonary Involvement
title_full_unstemmed IgA Vasculitis with Simultaneous Cardiopulmonary Involvement
title_short IgA Vasculitis with Simultaneous Cardiopulmonary Involvement
title_sort iga vasculitis with simultaneous cardiopulmonary involvement
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891522/
https://www.ncbi.nlm.nih.gov/pubmed/29225270
http://dx.doi.org/10.2169/internalmedicine.9681-17
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