Iron Deficiency Anemia Due to the Long-term Use of a Proton Pump Inhibitor

A 52-year-old man who had been taking omeprazole, a proton pump inhibitor (PPI), for 25 years developed iron deficiency anemia. An evaluation of the entire gastrointestinal tract did not reveal any possible causes of gastrointestinal blood loss. The cause of the iron deficiency was considered to be...

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Autores principales: Imai, Ryosuke, Higuchi, Takakazu, Morimoto, Masaya, Koyamada, Ryosuke, Okada, Sadamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891535/
https://www.ncbi.nlm.nih.gov/pubmed/29151538
http://dx.doi.org/10.2169/internalmedicine.9554-17
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author Imai, Ryosuke
Higuchi, Takakazu
Morimoto, Masaya
Koyamada, Ryosuke
Okada, Sadamu
author_facet Imai, Ryosuke
Higuchi, Takakazu
Morimoto, Masaya
Koyamada, Ryosuke
Okada, Sadamu
author_sort Imai, Ryosuke
collection PubMed
description A 52-year-old man who had been taking omeprazole, a proton pump inhibitor (PPI), for 25 years developed iron deficiency anemia. An evaluation of the entire gastrointestinal tract did not reveal any possible causes of gastrointestinal blood loss. The cause of the iron deficiency was considered to be a reduction in gastrointestinal iron absorption in association with the reduced secretion of gastric acid due to PPI use. This case demonstrates that long-term PPI use for as long as 25 years may cause iron deficiency anemia and should be considered in the differential diagnosis of iron deficiency anemia in long-term PPI users.
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spelling pubmed-58915352018-04-12 Iron Deficiency Anemia Due to the Long-term Use of a Proton Pump Inhibitor Imai, Ryosuke Higuchi, Takakazu Morimoto, Masaya Koyamada, Ryosuke Okada, Sadamu Intern Med Case Report A 52-year-old man who had been taking omeprazole, a proton pump inhibitor (PPI), for 25 years developed iron deficiency anemia. An evaluation of the entire gastrointestinal tract did not reveal any possible causes of gastrointestinal blood loss. The cause of the iron deficiency was considered to be a reduction in gastrointestinal iron absorption in association with the reduced secretion of gastric acid due to PPI use. This case demonstrates that long-term PPI use for as long as 25 years may cause iron deficiency anemia and should be considered in the differential diagnosis of iron deficiency anemia in long-term PPI users. The Japanese Society of Internal Medicine 2017-11-20 2018-03-15 /pmc/articles/PMC5891535/ /pubmed/29151538 http://dx.doi.org/10.2169/internalmedicine.9554-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Imai, Ryosuke
Higuchi, Takakazu
Morimoto, Masaya
Koyamada, Ryosuke
Okada, Sadamu
Iron Deficiency Anemia Due to the Long-term Use of a Proton Pump Inhibitor
title Iron Deficiency Anemia Due to the Long-term Use of a Proton Pump Inhibitor
title_full Iron Deficiency Anemia Due to the Long-term Use of a Proton Pump Inhibitor
title_fullStr Iron Deficiency Anemia Due to the Long-term Use of a Proton Pump Inhibitor
title_full_unstemmed Iron Deficiency Anemia Due to the Long-term Use of a Proton Pump Inhibitor
title_short Iron Deficiency Anemia Due to the Long-term Use of a Proton Pump Inhibitor
title_sort iron deficiency anemia due to the long-term use of a proton pump inhibitor
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891535/
https://www.ncbi.nlm.nih.gov/pubmed/29151538
http://dx.doi.org/10.2169/internalmedicine.9554-17
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