Cover Feature: Macromolecular Crowding May Significantly Affect the Performance of an MRI Contrast Agent: A (1)H NMR Spectroscopy, Microimaging, and Fast‐Field‐Cycling NMR Relaxometry Study (ChemistryOpen 4/2018)

The Cover Feature shows that macromolecular crowders PEG or BSA in an aqueous solution of a paramagnetic magnetic resonance imaging (MRI) contrast agent generally bring additional proton spin relaxation to the water molecules close to the paramagnetic ion and lead to contrast change in the MRI image...

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Autores principales: Cheng, Ren‐Hao, Chen, Jie‐Min, Chen, Yu‐Wen, Cai, Honghao, Cui, Xiaohong, Hwang, Dennis W., Chen, Zhong, Ding, Shangwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Cover Pictures
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891658/
http://dx.doi.org/10.1002/open.201800033
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author Cheng, Ren‐Hao
Chen, Jie‐Min
Chen, Yu‐Wen
Cai, Honghao
Cui, Xiaohong
Hwang, Dennis W.
Chen, Zhong
Ding, Shangwu
author_facet Cheng, Ren‐Hao
Chen, Jie‐Min
Chen, Yu‐Wen
Cai, Honghao
Cui, Xiaohong
Hwang, Dennis W.
Chen, Zhong
Ding, Shangwu
author_sort Cheng, Ren‐Hao
collection PubMed
description The Cover Feature shows that macromolecular crowders PEG or BSA in an aqueous solution of a paramagnetic magnetic resonance imaging (MRI) contrast agent generally bring additional proton spin relaxation to the water molecules close to the paramagnetic ion and lead to contrast change in the MRI images. This highlights the importance of considering the effect of macromolecular crowding on the performance of MRI contrast agents and image analysis, as well as diagnosis in clinical and functional MRI. More information can be found in the Full Paper on page 288 in Issue 4, 2018 by R.‐H. Cheng et al. (DOI: https://doi.org/10.1002/open.201700192).[Image: see text]
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spelling pubmed-58916582018-04-13 Cover Feature: Macromolecular Crowding May Significantly Affect the Performance of an MRI Contrast Agent: A (1)H NMR Spectroscopy, Microimaging, and Fast‐Field‐Cycling NMR Relaxometry Study (ChemistryOpen 4/2018) Cheng, Ren‐Hao Chen, Jie‐Min Chen, Yu‐Wen Cai, Honghao Cui, Xiaohong Hwang, Dennis W. Chen, Zhong Ding, Shangwu ChemistryOpen Cover Pictures The Cover Feature shows that macromolecular crowders PEG or BSA in an aqueous solution of a paramagnetic magnetic resonance imaging (MRI) contrast agent generally bring additional proton spin relaxation to the water molecules close to the paramagnetic ion and lead to contrast change in the MRI images. This highlights the importance of considering the effect of macromolecular crowding on the performance of MRI contrast agents and image analysis, as well as diagnosis in clinical and functional MRI. More information can be found in the Full Paper on page 288 in Issue 4, 2018 by R.‐H. Cheng et al. (DOI: https://doi.org/10.1002/open.201700192).[Image: see text] John Wiley and Sons Inc. 2018-03-25 /pmc/articles/PMC5891658/ http://dx.doi.org/10.1002/open.201800033 Text en © 2018 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim
spellingShingle Cover Pictures
Cheng, Ren‐Hao
Chen, Jie‐Min
Chen, Yu‐Wen
Cai, Honghao
Cui, Xiaohong
Hwang, Dennis W.
Chen, Zhong
Ding, Shangwu
Cover Feature: Macromolecular Crowding May Significantly Affect the Performance of an MRI Contrast Agent: A (1)H NMR Spectroscopy, Microimaging, and Fast‐Field‐Cycling NMR Relaxometry Study (ChemistryOpen 4/2018)
title Cover Feature: Macromolecular Crowding May Significantly Affect the Performance of an MRI Contrast Agent: A (1)H NMR Spectroscopy, Microimaging, and Fast‐Field‐Cycling NMR Relaxometry Study (ChemistryOpen 4/2018)
title_full Cover Feature: Macromolecular Crowding May Significantly Affect the Performance of an MRI Contrast Agent: A (1)H NMR Spectroscopy, Microimaging, and Fast‐Field‐Cycling NMR Relaxometry Study (ChemistryOpen 4/2018)
title_fullStr Cover Feature: Macromolecular Crowding May Significantly Affect the Performance of an MRI Contrast Agent: A (1)H NMR Spectroscopy, Microimaging, and Fast‐Field‐Cycling NMR Relaxometry Study (ChemistryOpen 4/2018)
title_full_unstemmed Cover Feature: Macromolecular Crowding May Significantly Affect the Performance of an MRI Contrast Agent: A (1)H NMR Spectroscopy, Microimaging, and Fast‐Field‐Cycling NMR Relaxometry Study (ChemistryOpen 4/2018)
title_short Cover Feature: Macromolecular Crowding May Significantly Affect the Performance of an MRI Contrast Agent: A (1)H NMR Spectroscopy, Microimaging, and Fast‐Field‐Cycling NMR Relaxometry Study (ChemistryOpen 4/2018)
title_sort cover feature: macromolecular crowding may significantly affect the performance of an mri contrast agent: a (1)h nmr spectroscopy, microimaging, and fast‐field‐cycling nmr relaxometry study (chemistryopen 4/2018)
topic Cover Pictures
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891658/
http://dx.doi.org/10.1002/open.201800033
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