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Macromolecular Crowding May Significantly Affect the Performance of an MRI Contrast Agent: A (1)H NMR Spectroscopy, Microimaging, and Fast‐Field‐Cycling NMR Relaxometry Study
Contrast enhancement agents are often employed in magnetic resonance imaging (MRI) for clinical diagnosis and biomedical research. However, the current theory on MRI contrast generation does not consider the ubiquitous presence of macromolecular crowders in biological systems, which poses the risk o...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891664/ https://www.ncbi.nlm.nih.gov/pubmed/29657915 http://dx.doi.org/10.1002/open.201700192 |