Macromolecular Crowding May Significantly Affect the Performance of an MRI Contrast Agent: A (1)H NMR Spectroscopy, Microimaging, and Fast‐Field‐Cycling NMR Relaxometry Study

Contrast enhancement agents are often employed in magnetic resonance imaging (MRI) for clinical diagnosis and biomedical research. However, the current theory on MRI contrast generation does not consider the ubiquitous presence of macromolecular crowders in biological systems, which poses the risk o...

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Detalles Bibliográficos
Autores principales: Cheng, Ren‐Hao, Chen, Jie‐Min, Chen, Yu‐Wen, Cai, Honghao, Cui, Xiaohong, Hwang, Dennis W., Chen, Zhong, Ding, Shangwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891664/
https://www.ncbi.nlm.nih.gov/pubmed/29657915
http://dx.doi.org/10.1002/open.201700192

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