Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment

BACKGROUND: Stromal gene expression patterns predict patient outcomes in colorectal cancer. TRIM28 is a transcriptional co-repressor that regulates an abundance of genes through the KRAB domain family of transcription factors. We have previously shown that stromal expression of TRIM28 is a marker of...

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Detalles Bibliográficos
Autores principales: Fitzgerald, Seán, Espina, Virginia, Liotta, Lance, Sheehan, Katherine M., O’Grady, Anthony, Cummins, Robert, O’Kennedy, Richard, Kay, Elaine W., Kijanka, Gregor S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891886/
https://www.ncbi.nlm.nih.gov/pubmed/29631612
http://dx.doi.org/10.1186/s12967-018-1465-z

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