Flagellin-fused protein targeting M2e and HA2 induces potent humoral and T-cell responses and protects mice against various influenza viruses a subtypes

BACKGROUND: Current influenza vaccines are mainly strain-specific and have limited efficacy in preventing new, potentially pandemic, influenza strains. Efficient control of influenza A infection can potentially be achieved through the development of broad-spectrum vaccines based on conserved antigen...

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Detalles Bibliográficos
Autores principales: Stepanova, Liudmila A., Mardanova, Eugenia S., Shuklina, Marina A., Blokhina, Elena A., Kotlyarov, Roman Y., Potapchuk, Marina V., Kovaleva, Anna A., Vidyaeva, Inna G., Korotkov, Alexandr V., Eletskaya, Elizaveta I., Ravin, Nikolai V., Tsybalova, Liudmila M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891888/
https://www.ncbi.nlm.nih.gov/pubmed/29631629
http://dx.doi.org/10.1186/s12929-018-0433-5

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