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Potential benefits of combining transfluthrin-treated sisal products and long-lasting insecticidal nets for controlling indoor-biting malaria vectors

BACKGROUND: Transfluthrin vapour prevents mosquito bites by disrupting their host-seeking behaviors. We measured the additional benefits of combining transfluthrin-treated sisal decorations and long-lasting insecticidal nets (LLINs) with an aim of extending protection against early evening, indoor-b...

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Autores principales: Masalu, John P., Okumu, Fredros O., Mmbando, Arnold S., Sikulu-Lord, Maggy T., Ogoma, Sheila B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891933/
https://www.ncbi.nlm.nih.gov/pubmed/29631633
http://dx.doi.org/10.1186/s13071-018-2811-y
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author Masalu, John P.
Okumu, Fredros O.
Mmbando, Arnold S.
Sikulu-Lord, Maggy T.
Ogoma, Sheila B.
author_facet Masalu, John P.
Okumu, Fredros O.
Mmbando, Arnold S.
Sikulu-Lord, Maggy T.
Ogoma, Sheila B.
author_sort Masalu, John P.
collection PubMed
description BACKGROUND: Transfluthrin vapour prevents mosquito bites by disrupting their host-seeking behaviors. We measured the additional benefits of combining transfluthrin-treated sisal decorations and long-lasting insecticidal nets (LLINs) with an aim of extending protection against early evening, indoor-biting malaria vectors when LLINs are ineffective. METHODS: We investigated the indoor protective efficacy of locally made sisal decorative baskets (0.28 m(2)) treated with 2.5 ml and 5.0 ml transfluthrin, in terms of mosquito density, exposure to bites and 24 h mortality. Experiments were conducted in experimental huts, located in Lupiro village, Ulanga District, south-eastern Tanzania. Human landing catches (HLC) were used to measure exposure to bites between 19:00–23:00 h. Each morning, at 06:00 h, mosquitoes were collected inside huts and in exit traps and monitored for 24 h mortality. RESULTS: Sisal decorative baskets (0.28 m(2)) treated with 2.5 ml and 5.0 ml transfluthrin deterred three-quarters of Anopheles arabiensis mosquitoes from entering huts (relative rate, RR = 0.26, 95% confidence interval, CI: 0.20–0.34, P < 0.001 and RR= 0.29, 95% CI: 0.22–0.37, P < 0.001, respectively). Both treatments induced a 10-fold increase in 24 h mortality of An. arabiensis mosquitoes (odds ratio, OR = 12.26, 95% CI: 7.70–19.51, P < 0.001 and OR = 18.42, 95% CI: 11.36–29.90, P < 0.001, respectively). CONCLUSIONS: Sisal decorative items treated with spatial repellents provide additional household and personal protection against indoor biting malaria and nuisance mosquitoes in the early evening, when conventional indoor vector control tools, such as LLINs, are not in use. We recommend future studies to investigate the epidemiological relevance of combining LLINs and transfluthrin decorated baskets in terms of their effect on reduction in malaria prevalence.
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spelling pubmed-58919332018-04-11 Potential benefits of combining transfluthrin-treated sisal products and long-lasting insecticidal nets for controlling indoor-biting malaria vectors Masalu, John P. Okumu, Fredros O. Mmbando, Arnold S. Sikulu-Lord, Maggy T. Ogoma, Sheila B. Parasit Vectors Research BACKGROUND: Transfluthrin vapour prevents mosquito bites by disrupting their host-seeking behaviors. We measured the additional benefits of combining transfluthrin-treated sisal decorations and long-lasting insecticidal nets (LLINs) with an aim of extending protection against early evening, indoor-biting malaria vectors when LLINs are ineffective. METHODS: We investigated the indoor protective efficacy of locally made sisal decorative baskets (0.28 m(2)) treated with 2.5 ml and 5.0 ml transfluthrin, in terms of mosquito density, exposure to bites and 24 h mortality. Experiments were conducted in experimental huts, located in Lupiro village, Ulanga District, south-eastern Tanzania. Human landing catches (HLC) were used to measure exposure to bites between 19:00–23:00 h. Each morning, at 06:00 h, mosquitoes were collected inside huts and in exit traps and monitored for 24 h mortality. RESULTS: Sisal decorative baskets (0.28 m(2)) treated with 2.5 ml and 5.0 ml transfluthrin deterred three-quarters of Anopheles arabiensis mosquitoes from entering huts (relative rate, RR = 0.26, 95% confidence interval, CI: 0.20–0.34, P < 0.001 and RR= 0.29, 95% CI: 0.22–0.37, P < 0.001, respectively). Both treatments induced a 10-fold increase in 24 h mortality of An. arabiensis mosquitoes (odds ratio, OR = 12.26, 95% CI: 7.70–19.51, P < 0.001 and OR = 18.42, 95% CI: 11.36–29.90, P < 0.001, respectively). CONCLUSIONS: Sisal decorative items treated with spatial repellents provide additional household and personal protection against indoor biting malaria and nuisance mosquitoes in the early evening, when conventional indoor vector control tools, such as LLINs, are not in use. We recommend future studies to investigate the epidemiological relevance of combining LLINs and transfluthrin decorated baskets in terms of their effect on reduction in malaria prevalence. BioMed Central 2018-04-10 /pmc/articles/PMC5891933/ /pubmed/29631633 http://dx.doi.org/10.1186/s13071-018-2811-y Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Masalu, John P.
Okumu, Fredros O.
Mmbando, Arnold S.
Sikulu-Lord, Maggy T.
Ogoma, Sheila B.
Potential benefits of combining transfluthrin-treated sisal products and long-lasting insecticidal nets for controlling indoor-biting malaria vectors
title Potential benefits of combining transfluthrin-treated sisal products and long-lasting insecticidal nets for controlling indoor-biting malaria vectors
title_full Potential benefits of combining transfluthrin-treated sisal products and long-lasting insecticidal nets for controlling indoor-biting malaria vectors
title_fullStr Potential benefits of combining transfluthrin-treated sisal products and long-lasting insecticidal nets for controlling indoor-biting malaria vectors
title_full_unstemmed Potential benefits of combining transfluthrin-treated sisal products and long-lasting insecticidal nets for controlling indoor-biting malaria vectors
title_short Potential benefits of combining transfluthrin-treated sisal products and long-lasting insecticidal nets for controlling indoor-biting malaria vectors
title_sort potential benefits of combining transfluthrin-treated sisal products and long-lasting insecticidal nets for controlling indoor-biting malaria vectors
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891933/
https://www.ncbi.nlm.nih.gov/pubmed/29631633
http://dx.doi.org/10.1186/s13071-018-2811-y
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