Investigation into the role of the germline epigenome in the transmission of glucocorticoid-programmed effects across generations

BACKGROUND: Early life exposure to adverse environments affects cardiovascular and metabolic systems in the offspring. These programmed effects are transmissible to a second generation through both male and female lines, suggesting germline transmission. We have previously shown that prenatal overex...

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Detalles Bibliográficos
Autores principales: Cartier, Jessy, Smith, Thomas, Thomson, John P., Rose, Catherine M., Khulan, Batbayar, Heger, Andreas, Meehan, Richard R., Drake, Amanda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891941/
https://www.ncbi.nlm.nih.gov/pubmed/29636086
http://dx.doi.org/10.1186/s13059-018-1422-4

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