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Transcriptional activator DOT1L putatively regulates human embryonic stem cell differentiation into the cardiac lineage
BACKGROUND: Commitment of pluripotent stem cells into differentiated cells and associated gene expression necessitate specific epigenetic mechanisms that modify the DNA and corresponding histone proteins to render the chromatin in an open or closed state. This in turn dictates the associated genetic...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891944/ https://www.ncbi.nlm.nih.gov/pubmed/29631608 http://dx.doi.org/10.1186/s13287-018-0810-8 |