Cargando…

Beneficial Effects of Resveratrol-Mediated Inhibition of the mTOR Pathway in Spinal Cord Injury

Spinal cord injury (SCI) causes a high rate of morbidity and disability. The clinical features of SCI are divided into acute, subacute, and chronic phases according to its pathophysiological events. The mammalian target of rapamycin (mTOR) signaling pathway plays an important role in cell death and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Jingying, Huo, Xue, Botchway, Benson O. A., Xu, Luyao, Meng, Xiaofang, Zhang, Songou, Liu, Xuehong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892236/ https://www.ncbi.nlm.nih.gov/pubmed/29780409 http://dx.doi.org/10.1155/2018/7513748

Ejemplares similares

Inhibition of NF-κB Signaling Pathway by Resveratrol Improves Spinal Cord Injury
por: Xu, Luyao, et al.
Publicado: (2018)

Quercetin Can Improve Spinal Cord Injury by Regulating the mTOR Signaling Pathway
por: Wang, Xichen, et al.
Publicado: (2022)

“mTOR Signaling Pathway”: A Potential Target of Curcumin in the Treatment of Spinal Cord Injury
por: Lin, Jingquan, et al.
Publicado: (2017)

Resveratrol Can Attenuate Astrocyte Activation to Treat Spinal Cord Injury by Inhibiting Inflammatory Responses
por: Fan, Ruihua, et al.
Publicado: (2021)

Combinational Treatment of Bioscaffolds and Extracellular Vesicles in Spinal Cord Injury
por: Wang, Xizhi, et al.
Publicado: (2019)

The Repression of the HMGB1-TLR4-NF-κB Signaling Pathway by Safflower Yellow May Improve Spinal Cord Injury
por: Wang, Lu, et al.
Publicado: (2021)

Blocking mammalian target of rapamycin (mTOR) improves neuropathic pain evoked by spinal cord injury
por: Wang, Xiaoping, et al.
Publicado: (2016)

Involvement of mTOR Pathways in Recovery from Spinal Cord Injury by Modulation of Autophagy and Immune Response
por: Vargova, Ingrid, et al.
Publicado: (2021)

Resveratrol induces autophagy by directly inhibiting mTOR through ATP competition
por: Park, Dohyun, et al.
Publicado: (2016)

Role of Spinal Cord Akt-mTOR Signaling Pathways in Postoperative Hyperalgesia Induced by Plantar Incision in Mice
por: Xu, Bing, et al.
Publicado: (2020)

Protective role of ethyl pyruvate in spinal cord injury by inhibiting the high mobility group box-1/toll-like receptor4/nuclear factor-kappa B signaling pathway
por: Fan, Ruihua, et al.
Publicado: (2022)

Akt/mTOR Targeting Activity of Resveratrol Derivatives in Non-Small Lung Cancer
por: Innets, Bhurichaya, et al.
Publicado: (2022)

Systemic Bisperoxovanadium Activates Akt/mTOR, Reduces Autophagy, and Enhances Recovery following Cervical Spinal Cord Injury
por: Walker, Chandler L., et al.
Publicado: (2012)

mTOR Pathway and mTOR Inhibitors in Head and Neck Cancer
por: Gao, Wei, et al.
Publicado: (2012)

Immunomodulatory and Antiaging Mechanisms of Resveratrol, Rapamycin, and Metformin: Focus on mTOR and AMPK Signaling Networks
por: Sorrenti, Vincenzo, et al.
Publicado: (2022)

Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway
por: Wu, Chenyu, et al.
Publicado: (2021)

Trehalose Augments Neuron Survival and Improves Recovery from Spinal Cord Injury via mTOR-Independent Activation of Autophagy
por: Zhou, Kailiang, et al.
Publicado: (2021)

Myelination and mTOR
por: Figlia, Gianluca, et al.
Publicado: (2017)

Resveratrol, an activator of SIRT1, induces protective autophagy in non-small-cell lung cancer via inhibiting Akt/mTOR and activating p38-MAPK
por: Wang, Jing, et al.
Publicado: (2018)

mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges
por: Zou, Zhilin, et al.
Publicado: (2020)

Effects of Resveratrol, Lovastatin and the mTOR-Inhibitor RAD-001 on Insulin-Induced Genomic Damage In Vitro
por: Awad, Eman, et al.
Publicado: (2017)

The role of the miR-99b-5p/mTOR signaling pathway in neuroregeneration in mice following spinal cord injury
por: Cao, Fujiang, et al.
Publicado: (2017)

Buyang Huanwu decoction improves neural recovery after spinal cord injury in rats through the mTOR signaling pathway and autophagy
por: Nie, Ying, et al.
Publicado: (2021)

mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy
por: Tian, Tian, et al.
Publicado: (2019)

Regulation of Osteoclast Growth and Fusion by mTOR/raptor and mTOR/rictor/Akt
por: Tiedemann, Kerstin, et al.
Publicado: (2017)

Escaping mTOR inhibition for cancer therapy: Tumor suppressor functions of mTOR
por: Villar, Victor H., et al.
Publicado: (2017)

Overcoming mTOR Resistance Mutations with a New Generation mTOR Inhibitor
por: Rodrik-Outmezguine, Vanessa S., et al.
Publicado: (2016)

The Role of mTOR and Injury in Developing Salispheres
por: Saleem, Rimah, et al.
Publicado: (2023)

mTOR and lysosome regulation
por: Puertollano, Rosa
Publicado: (2014)

mTOR, autophagy, and reprogramming
por: Tang, Bor Luen
Publicado: (2014)

Targeting glutaminase and mTOR
por: Tanaka, Kazuhiro, et al.
Publicado: (2015)

mTOR in cerebrovascular disease
por: Van Skike, Candice E., et al.
Publicado: (2019)

mTOR and Tumor Cachexia
por: Duval, Adrian P., et al.
Publicado: (2018)

Double agent mTOR
por: Danzer, Steve C.
Publicado: (2019)

mTOR in Human Diseases
por: Dormond, Olivier
Publicado: (2019)

Commentary: Overcoming mTOR resistance mutations with a new-generation mTOR inhibitor
por: Renna, Maurizio
Publicado: (2016)

Netrin-1 Improves Functional Recovery through Autophagy Regulation by Activating the AMPK/mTOR Signaling Pathway in Rats with Spinal Cord Injury
por: Bai, Liangjie, et al.
Publicado: (2017)

Gypenoside XVII protects against spinal cord injury in mice by regulating the microRNA-21-mediated PTEN/AKT/mTOR pathway
por: Sun, Tianyu, et al.
Publicado: (2021)

Resveratrol enhances prostate cancer cell response to ionizing radiation. Modulation of the AMPK, Akt and mTOR pathways
por: Rashid, Ayesha, et al.
Publicado: (2011)

Expression of mTOR/70S6K signaling pathway in pathological scar fibroblasts and the effects of resveratrol intervention
por: Tang, Zhi-Ming, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_4js4ai7dufcihf50ll8brrbunm