Cargando…
Withaferin A is a Leptin Sensitizer with Strong Anti-Diabetic Properties in Mice
The increasing global prevalence of obesity and its associated disorders point to an urgent need for the development of novel and effective therapeutic strategies that induce healthy weight loss. Obesity is characterized by hyperleptinemia and central leptin resistance. In an attempt to identify com...
Autores principales: | Lee, Jaemin, Liu, Junli, Feng, Xudong, Salazar Hernández, Mario Andrés, Mucka, Patrick, Ibi, Dorina, Choi, Jae Won, Ozcan, Umut |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892415/ https://www.ncbi.nlm.nih.gov/pubmed/27479085 http://dx.doi.org/10.1038/nm.4145 |
Ejemplares similares
-
IL1R1 is required for celastrol’s leptin sensitization and anti-obesity effects
por: Feng, Xudong, et al.
Publicado: (2019) -
PGC-1α functions as a co-suppressor of XBP1s to regulate glucose metabolism
por: Lee, Jaemin, et al.
Publicado: (2017) -
Implications of Withaferin A in neurological disorders
por: Ram, Natasha, et al.
Publicado: (2020) -
Lipocalin 2 Does Not Play A Role in Celastrol-Mediated Reduction in Food Intake and Body Weight
por: Feng, Xudong, et al.
Publicado: (2019) -
SUN-096 Hypothalamic ATP Has a Crucial Role in the Pathogenesis of Leptin Resistance: A Potential Mechanism for the Amelioration of Leptin Resistance by Celastrol and Withaferin A
por: Ebihara, Chihiro, et al.
Publicado: (2019)