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CD40L promotes development of acute aortic dissection via induction of inflammation and impairment of endothelial cell function

Acute aortic dissection is one of the most lethal cardiovascular disease. The major histopathological feature of AAD is medial degradation, especially breakdown of elastin and collagen. However, the underlying mechanism remains a mystery. Platelets expressed CD40 Ligand (CD40L) is recently recognise...

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Detalles Bibliográficos
Autores principales: Han, Lu, Dai, Lu, Zhao, Yuan-Fei, Li, Hai-Yang, Liu, Ou, Lan, Feng, Jiang, Wen-Jian, Zhang, Hong-Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892687/
https://www.ncbi.nlm.nih.gov/pubmed/29514135
http://dx.doi.org/10.18632/aging.101394