Chromothripsis in Acute Myeloid Leukemia: biological features and impact on survival

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Chromothripsis is a one-step genome-shattering catastrophe resulting from disruption of one or few chromosomes in multiple fragments and consequent random rejoining and repair. This study define incidence of chromothripsis in 395 newly-diagnosed adult acute myeloid leukemia (AML) patients from three...

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Detalles Bibliográficos
Autores principales: Fontana, Maria Chiara, Marconi, Giovanni, Milosevic Feenstra, Jelena D., Fonzi, Eugenio, Papayannidis, Cristina, Ghelli Luserna di Rorá, Andrea, Padella, Antonella, Solli, Vincenza, Franchini, Eugenia, Ottaviani, Emanuela, Ferrari, Anna, Baldazzi, Carmen, Testoni, Nicoletta, Iacobucci, Ilaria, Soverini, Simona, Haferlach, Torsten, Guadagnuolo, Viviana, Semerad, Lukas, Doubek, Michael, Steurer, Michael, Racil, Zdenek, Paolini, Stefania, Manfrini, Marco, Cavo, Michele, Simonetti, Giorgia, Kralovics, Robert, Martinelli, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892717/
http://dx.doi.org/10.1038/leu.2017.351
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