Exploiting distant homologues for phasing through the generation of compact fragments, local fold refinement and partial solution combination

Macromolecular structures can be solved by molecular replacement provided that suitable search models are available. Models from distant homologues may deviate too much from the target structure to succeed, notwithstanding an overall similar fold or even their featuring areas of very close geometry....

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Detalles Bibliográficos
Autores principales: Millán, Claudia, Sammito, Massimo Domenico, McCoy, Airlie J., Nascimento, Andrey F. Ziem, Petrillo, Giovanna, Oeffner, Robert D., Domínguez-Gil, Teresa, Hermoso, Juan A., Read, Randy J., Usón, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2018
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892878/
https://www.ncbi.nlm.nih.gov/pubmed/29652256
http://dx.doi.org/10.1107/S2059798318001365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892878/
https://www.ncbi.nlm.nih.gov/pubmed/29652256
http://dx.doi.org/10.1107/S2059798318001365

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