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Exploiting distant homologues for phasing through the generation of compact fragments, local fold refinement and partial solution combination
Macromolecular structures can be solved by molecular replacement provided that suitable search models are available. Models from distant homologues may deviate too much from the target structure to succeed, notwithstanding an overall similar fold or even their featuring areas of very close geometry....
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892878/ https://www.ncbi.nlm.nih.gov/pubmed/29652256 http://dx.doi.org/10.1107/S2059798318001365 |