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Core lipid, surface lipid and apolipoprotein composition analysis of lipoprotein particles as a function of particle size in one workflow integrating asymmetric flow field-flow fractionation and liquid chromatography-tandem mass spectrometry
Lipoproteins are complex molecular assemblies that are key participants in the intricate cascade of extracellular lipid metabolism with important consequences in the formation of atherosclerotic lesions and the development of cardiovascular disease. Multiplexed mass spectrometry (MS) techniques have...
Autores principales: | Kuklenyik, Zsuzsanna, Jones, Jeffery I., Gardner, Michael S., Schieltz, David M., Parks, Bryan A., Toth, Christopher A., Rees, Jon C., Andrews, Michael L., Carter, Kayla, Lehtikoski, Antony K., McWilliams, Lisa G., Williamson, Yulanda M., Bierbaum, Kevin P., Pirkle, James L., Barr, John R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892890/ https://www.ncbi.nlm.nih.gov/pubmed/29634782 http://dx.doi.org/10.1371/journal.pone.0194797 |
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