Cargando…
The colonic epithelium plays an active role in promoting colitis by shaping the tissue cytokine profile
Inflammatory bowel disease (IBD) is a chronic condition driven by loss of homeostasis between the mucosal immune system, the commensal gut microbiota, and the intestinal epithelium. Our goal is to understand how these components of the intestinal ecosystem cooperate to control homeostasis. By combin...
Autores principales: | Lyons, Jesse, Ghazi, Phaedra C., Starchenko, Alina, Tovaglieri, Alessio, Baldwin, Katherine R., Poulin, Emily J., Gierut, Jessica J., Genetti, Casie, Yajnik, Vijay, Breault, David T., Lauffenburger, Douglas A., Haigis, Kevin M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892915/ https://www.ncbi.nlm.nih.gov/pubmed/29596476 http://dx.doi.org/10.1371/journal.pbio.2002417 |
Ejemplares similares
-
Distinct Processes and Transcriptional Targets Underlie CDX2 Requirements in Intestinal Stem Cells and Differentiated Villus Cells
por: San Roman, Adrianna K., et al.
Publicado: (2015) -
Multi-Scale In Vivo Systems Analysis Reveals the Influence of Immune Cells on TNF-α-Induced Apoptosis in the Intestinal Epithelium
por: Lau, Ken S., et al.
Publicado: (2012) -
Correction: Multi-Scale In Vivo Systems Analysis Reveals the Influence of Immune Cells on TNF-α-Induced Apoptosis in the Intestinal Epithelium
por: Lau, Ken S., et al.
Publicado: (2012) -
Cross-species transcriptomic signatures predict response to MK2 inhibition in mouse models of chronic inflammation
por: Suarez-Lopez, Lucia, et al.
Publicado: (2021) -
JAK/STAT-1 Signaling Is Required for Reserve Intestinal Stem Cell Activation during Intestinal Regeneration Following Acute Inflammation
por: Richmond, Camilla A., et al.
Publicado: (2017)