The (95)RGD(97) sequence on the Aα chain of fibrinogen is essential for binding to its erythrocyte receptor

BACKGROUND: Erythrocyte aggregation, a cardiovascular risk factor, is increased by high plasma fibrinogen levels. Here, the effect of different fibrinogen mutations on binding to its human erythrocyte receptor was assessed in order to identify the interaction sites. METHODS: Three fibrinogen variant...

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Detalles Bibliográficos
Autores principales: Carvalho, Filomena A, Guedes, Ana Filipa, Duval, Cedric, Macrae, Fraser L, Swithenbank, Luke, Farrell, David H, Ariëns, Robert AS, Santos, Nuno C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892956/
https://www.ncbi.nlm.nih.gov/pubmed/29662311
http://dx.doi.org/10.2147/IJN.S154523

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