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Induced global deletion of glucocorticoid receptor impairs fracture healing
Although endogenous glucocorticoids (GCs) are important regulators of bone integrity and the immune system, their role in bone repair after fracture—a process highly dependent on inflammation and bone formation—is unclear. Because most effects of GCs are mediated by the glucocorticoid receptor (GR),...
Autores principales: | Rapp, Anna E., Hachemi, Yasmine, Kemmler, Julia, Koenen, Mascha, Tuckermann, Jan, Ignatius, Anita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Federation of American Societies for Experimental Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893166/ https://www.ncbi.nlm.nih.gov/pubmed/29217668 http://dx.doi.org/10.1096/fj.201700459RR |
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