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Induced global deletion of glucocorticoid receptor impairs fracture healing

Although endogenous glucocorticoids (GCs) are important regulators of bone integrity and the immune system, their role in bone repair after fracture—a process highly dependent on inflammation and bone formation—is unclear. Because most effects of GCs are mediated by the glucocorticoid receptor (GR),...

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Detalles Bibliográficos
Autores principales: Rapp, Anna E., Hachemi, Yasmine, Kemmler, Julia, Koenen, Mascha, Tuckermann, Jan, Ignatius, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893166/
https://www.ncbi.nlm.nih.gov/pubmed/29217668
http://dx.doi.org/10.1096/fj.201700459RR

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