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Cross resistance to diverse anticancer nicotinamide phosphoribosyltransferase inhibitors induced by FK866 treatment

Cross-resistance to drugs remains an unsolved problem in cancer chemotherapy. This study elucidates a molecular mechanism of cross-resistance to diverse inhibitors of nicotinamide phosphoribosyltransferase (NAMPT) with anticancer activity. We generated a variant of the human colon cancer cell line H...

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Detalles Bibliográficos
Autores principales: Ogino, Yoko, Sato, Akira, Uchiumi, Fumiaki, Tanuma, Sei-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893253/
https://www.ncbi.nlm.nih.gov/pubmed/29662658
http://dx.doi.org/10.18632/oncotarget.24731

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