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ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration

Age-related macular degeneration (AMD) is a significant cause of vision loss in the elderly. The extent to which epigenetic changes regulate AMD progression is unclear. Here we globally profile chromatin accessibility using ATAC-Seq in the retina and retinal pigmented epithelium (RPE) from AMD and c...

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Detalles Bibliográficos
Autores principales:	Wang, Jie, Zibetti, Cristina, Shang, Peng, Sripathi, Srinivasa R., Zhang, Pingwu, Cano, Marisol, Hoang, Thanh, Xia, Shuli, Ji, Hongkai, Merbs, Shannath L., Zack, Donald J., Handa, James T., Sinha, Debasish, Blackshaw, Seth, Qian, Jiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893535/ https://www.ncbi.nlm.nih.gov/pubmed/29636475 http://dx.doi.org/10.1038/s41467-018-03856-y

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