Transposon-modified antigen-specific T lymphocytes for sustained therapeutic protein delivery in vivo

A cell therapy platform permitting long-term delivery of peptide hormones in vivo would be a significant advance for patients with hormonal deficiencies. Here we report the utility of antigen-specific T lymphocytes as a regulatable peptide delivery platform for in vivo therapy. piggyBac transposon m...

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Detalles Bibliográficos
Autores principales: O’Neil, Richard T., Saha, Sunandan, Veach, Ruth Ann, Welch, Richard C., Woodard, Lauren E., Rooney, Cliona M., Wilson, Matthew H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893599/
https://www.ncbi.nlm.nih.gov/pubmed/29636469
http://dx.doi.org/10.1038/s41467-018-03787-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893599/
https://www.ncbi.nlm.nih.gov/pubmed/29636469
http://dx.doi.org/10.1038/s41467-018-03787-8

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