Cargando…
DNA-release by Streptococcus pneumoniae autolysin LytA induced Krueppel-like factor 4 expression in macrophages
The recruitment of myeloid cells to the lung is of utmost importance for the elimination of invading pathogens. We investigated the Streptococcus pneumoniae-dependent induction mechanism of KLF4 in macrophages as a potential regulator of the macrophage immune response. We demonstrated that only viab...
Autores principales: | Herta, Toni, Bhattacharyya, Aritra, Bollensdorf, Christian, Kabus, Christin, García, Pedro, Suttorp, Norbert, Hippenstiel, Stefan, Zahlten, Janine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893607/ https://www.ncbi.nlm.nih.gov/pubmed/29636524 http://dx.doi.org/10.1038/s41598-018-24152-1 |
Ejemplares similares
-
LytA, Major Autolysin of Streptococcus pneumoniae, Requires Access to Nascent Peptidoglycan
por: Mellroth, Peter, et al.
Publicado: (2012) -
Krueppel-Like Factor 4 Expression in Phagocytes Regulates Early Inflammatory Response and Disease Severity in Pneumococcal Pneumonia
por: Herta, Toni, et al.
Publicado: (2021) -
Dynamic capsule restructuring by the main pneumococcal autolysin LytA in response to the epithelium
por: Kietzman, Colin C., et al.
Publicado: (2016) -
Insights into the Evolutionary Relationships of LytA Autolysin and Ply Pneumolysin-Like Genes in Streptococcus pneumoniae and Related Streptococci
por: Morales, María, et al.
Publicado: (2015) -
Induction of Krüppel-Like Factor 4 Mediates Polymorphonuclear Neutrophil Activation in Streptococcus pneumoniae Infection
por: Bhattacharyya, Aritra, et al.
Publicado: (2021)