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On the contributing role of the transmembrane domain for subunit-specific sensitivity of integrin activation
Integrins are α/β heterodimeric transmembrane adhesion receptors. Evidence exists that their transmembrane domain (TMD) separates upon activation. Subunit-specific differences in activation sensitivity of integrins were reported. However, whether sequence variations in the TMD lead to differential T...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893634/ https://www.ncbi.nlm.nih.gov/pubmed/29636500 http://dx.doi.org/10.1038/s41598-018-23778-5 |