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Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors

Tumor necrosis factor-α (TNF-α) plays a pivotal role in inflammatory response. Dysregulation of TNF can lead to a variety of disastrous pathological effects, including auto-inflammatory diseases. Antibodies that directly targeting TNF-α have been proven effective in suppressing symptoms of these dis...

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Detalles Bibliográficos
Autores principales:	Deng, Xiaobing, Zhang, Xiaoling, Tang, Bo, Liu, Hongbo, Shen, Qi, Liu, Ying, Lai, Luhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893771/ https://www.ncbi.nlm.nih.gov/pubmed/29670876 http://dx.doi.org/10.3389/fchem.2018.00098

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