Cargando…
Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease
Gene-based tests to study the combined effect of rare variants on a particular phenotype have been widely developed for case-control studies, but their evolution and adaptation for family-based studies, especially studies of complex incomplete families, has been slower. In this study, we have perfor...
Autores principales: | Fernández, Maria V., Budde, John, Del-Aguila, Jorge L., Ibañez, Laura, Deming, Yuetiva, Harari, Oscar, Norton, Joanne, Morris, John C., Goate, Alison M., Cruchaga, Carlos |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893779/ https://www.ncbi.nlm.nih.gov/pubmed/29670507 http://dx.doi.org/10.3389/fnins.2018.00209 |
Ejemplares similares
-
Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease
por: Fernández, Maria Victoria, et al.
Publicado: (2017) -
Genome-wide association study for variants that modulate relationships between cerebrospinal fluid amyloid-beta 42, tau, and p-tau levels
por: Maxwell, Taylor J., et al.
Publicado: (2018) -
Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer’s disease brains
por: Novotny, Brenna C., et al.
Publicado: (2023) -
Haplotype-based association analysis of the MAPT locus in Late Onset Alzheimer's disease
por: Mukherjee, Odity, et al.
Publicado: (2007) -
The National Institute on Aging Late‐Onset Alzheimer's Disease Family Based Study: A resource for genetic discovery
por: Reyes‐Dumeyer, Dolly, et al.
Publicado: (2022)