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Overactivity of Alternative Pathway Convertases in Patients With Complement-Mediated Renal Diseases

Overactivation of the alternative pathway of the complement system is associated with the renal diseases atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G). C3 nephritic factors (C3NeF) play an important role in C3G pathogenesis by stabilizing the key enzymatic complex of compleme...

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Detalles Bibliográficos
Autores principales:	Michels, Marloes A. H. M., van de Kar, Nicole C. A. J., Okrój, Marcin, Blom, Anna M., van Kraaij, Sanne A. W., Volokhina, Elena B., van den Heuvel, Lambertus P. W. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893837/ https://www.ncbi.nlm.nih.gov/pubmed/29670616 http://dx.doi.org/10.3389/fimmu.2018.00612

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