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A New Age-Structured Multiscale Model of the Hepatitis C Virus Life-Cycle During Infection and Therapy With Direct-Acting Antiviral Agents

The dynamics of hepatitis C virus (HCV) RNA during translation and replication within infected cells were added to a previous age-structured multiscale mathematical model of HCV infection and treatment. The model allows the study of the dynamics of HCV RNA inside infected cells as well as the releas...

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Detalles Bibliográficos
Autores principales:	Quintela, Barbara de M., Conway, Jessica M., Hyman, James M., Guedj, Jeremie, dos Santos, Rodrigo W., Lobosco, Marcelo, Perelson, Alan S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893852/ https://www.ncbi.nlm.nih.gov/pubmed/29670586 http://dx.doi.org/10.3389/fmicb.2018.00601

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