Cargando…

Inter-Observer Agreement of Whole-Body Computed Tomography in Staging and Response Assessment in Lymphoma: The Lugano Classification

BACKGROUND: To assess inter-observer agreement of whole-body computed tomography (WBCT) in staging and response assessment in lymphoma according to the Lugano classification. MATERIAL/METHODS: Retrospective analysis was conducted of 115 consecutive patients with lymphomas (45 females, 70 males; mean...

Descripción completa

Detalles Bibliográficos
Autores principales: Razek, Ahmed Abdel Khalek Abdel, Shamaa, Sameh, Lattif, Mahmoud Abdel, Yousef, Hanan Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894009/
https://www.ncbi.nlm.nih.gov/pubmed/29662570
http://dx.doi.org/10.12659/PJR.902370
_version_ 1783313415182221312
author Razek, Ahmed Abdel Khalek Abdel
Shamaa, Sameh
Lattif, Mahmoud Abdel
Yousef, Hanan Hamid
author_facet Razek, Ahmed Abdel Khalek Abdel
Shamaa, Sameh
Lattif, Mahmoud Abdel
Yousef, Hanan Hamid
author_sort Razek, Ahmed Abdel Khalek Abdel
collection PubMed
description BACKGROUND: To assess inter-observer agreement of whole-body computed tomography (WBCT) in staging and response assessment in lymphoma according to the Lugano classification. MATERIAL/METHODS: Retrospective analysis was conducted of 115 consecutive patients with lymphomas (45 females, 70 males; mean age of 46 years). Patients underwent WBCT with a 64 multi-detector CT device for staging and response assessment after a complete course of chemotherapy. Image analysis was performed by 2 reviewers according to the Lugano classification for staging and response assessment. RESULTS: The overall inter-observer agreement of WBCT in staging of lymphoma was excellent (k=0.90, percent agreement=94.9%). There was an excellent inter-observer agreement for stage I (k=0.93, percent agreement=96.4%), stage II (k=0.90, percent agreement=94.8%), stage III (k=0.89, percent agreement=94.6%) and stage IV (k=0.88, percent agreement=94%). The overall inter-observer agreement in response assessment after a completer course of treatment was excellent (k=0.91, percent agreement=95.8%). There was an excellent inter-observer agreement in progressive disease (k=0.94, percent agreement=97.1%), stable disease (k=0.90, percent agreement=95%), partial response (k=0.96, percent agreement=98.1%) and complete response (k=0.87, Percent agreement=93.3%). CONCLUSIONS: We concluded that WBCT is a reliable and reproducible imaging modality for staging and treatment assessment in lymphoma according to the Lugano classification.
format Online
Article
Text
id pubmed-5894009
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Termedia Publishing House
record_format MEDLINE/PubMed
spelling pubmed-58940092018-04-16 Inter-Observer Agreement of Whole-Body Computed Tomography in Staging and Response Assessment in Lymphoma: The Lugano Classification Razek, Ahmed Abdel Khalek Abdel Shamaa, Sameh Lattif, Mahmoud Abdel Yousef, Hanan Hamid Pol J Radiol Original Article BACKGROUND: To assess inter-observer agreement of whole-body computed tomography (WBCT) in staging and response assessment in lymphoma according to the Lugano classification. MATERIAL/METHODS: Retrospective analysis was conducted of 115 consecutive patients with lymphomas (45 females, 70 males; mean age of 46 years). Patients underwent WBCT with a 64 multi-detector CT device for staging and response assessment after a complete course of chemotherapy. Image analysis was performed by 2 reviewers according to the Lugano classification for staging and response assessment. RESULTS: The overall inter-observer agreement of WBCT in staging of lymphoma was excellent (k=0.90, percent agreement=94.9%). There was an excellent inter-observer agreement for stage I (k=0.93, percent agreement=96.4%), stage II (k=0.90, percent agreement=94.8%), stage III (k=0.89, percent agreement=94.6%) and stage IV (k=0.88, percent agreement=94%). The overall inter-observer agreement in response assessment after a completer course of treatment was excellent (k=0.91, percent agreement=95.8%). There was an excellent inter-observer agreement in progressive disease (k=0.94, percent agreement=97.1%), stable disease (k=0.90, percent agreement=95%), partial response (k=0.96, percent agreement=98.1%) and complete response (k=0.87, Percent agreement=93.3%). CONCLUSIONS: We concluded that WBCT is a reliable and reproducible imaging modality for staging and treatment assessment in lymphoma according to the Lugano classification. Termedia Publishing House 2017-08-23 /pmc/articles/PMC5894009/ /pubmed/29662570 http://dx.doi.org/10.12659/PJR.902370 Text en Copyright © Polish Medical Society of Radiology 2017 https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0). License allowing third parties to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
spellingShingle Original Article
Razek, Ahmed Abdel Khalek Abdel
Shamaa, Sameh
Lattif, Mahmoud Abdel
Yousef, Hanan Hamid
Inter-Observer Agreement of Whole-Body Computed Tomography in Staging and Response Assessment in Lymphoma: The Lugano Classification
title Inter-Observer Agreement of Whole-Body Computed Tomography in Staging and Response Assessment in Lymphoma: The Lugano Classification
title_full Inter-Observer Agreement of Whole-Body Computed Tomography in Staging and Response Assessment in Lymphoma: The Lugano Classification
title_fullStr Inter-Observer Agreement of Whole-Body Computed Tomography in Staging and Response Assessment in Lymphoma: The Lugano Classification
title_full_unstemmed Inter-Observer Agreement of Whole-Body Computed Tomography in Staging and Response Assessment in Lymphoma: The Lugano Classification
title_short Inter-Observer Agreement of Whole-Body Computed Tomography in Staging and Response Assessment in Lymphoma: The Lugano Classification
title_sort inter-observer agreement of whole-body computed tomography in staging and response assessment in lymphoma: the lugano classification
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894009/
https://www.ncbi.nlm.nih.gov/pubmed/29662570
http://dx.doi.org/10.12659/PJR.902370
work_keys_str_mv AT razekahmedabdelkhalekabdel interobserveragreementofwholebodycomputedtomographyinstagingandresponseassessmentinlymphomatheluganoclassification
AT shamaasameh interobserveragreementofwholebodycomputedtomographyinstagingandresponseassessmentinlymphomatheluganoclassification
AT lattifmahmoudabdel interobserveragreementofwholebodycomputedtomographyinstagingandresponseassessmentinlymphomatheluganoclassification
AT yousefhananhamid interobserveragreementofwholebodycomputedtomographyinstagingandresponseassessmentinlymphomatheluganoclassification