Application of Intravoxel Incoherent Motion (IVIM) Model for Differentiation Between Metastatic and Non-Metastatic Head and Neck Lymph Nodes

BACKGROUND: Application of intravoxel incoherent motion (IVIM) model parameters, including: true diffusion (D), pseudodiffusion (D*), and perfusion fraction (F(p)), for differentiation between metastatic and non-metastatic head and neck lymph nodes. MATERIAL/METHODS: Diffusion-weighted images/appare...

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Detalles Bibliográficos
Autores principales: Hejduk, Beata, Bobek-Billewicz, Barbara, Rutkowski, Tomasz, Hebda, Anna, Zawadzka, Agata, Jurkowski, Marek K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894025/
https://www.ncbi.nlm.nih.gov/pubmed/29662580
http://dx.doi.org/10.12659/PJR.902275
Descripción
Sumario:BACKGROUND: Application of intravoxel incoherent motion (IVIM) model parameters, including: true diffusion (D), pseudodiffusion (D*), and perfusion fraction (F(p)), for differentiation between metastatic and non-metastatic head and neck lymph nodes. MATERIAL/METHODS: Diffusion-weighted images/apparent diffusion coefficient (DWI/ADC) images of 86 lymph nodes from 31 cancer patients were analyzed. DWI images were obtained with a 1.5T MRI scanner (Magnetom Avanto); b=0,50, 150, 300, 500, 750, 1000, 1200 s/mm(2). RESULTS: In the study group, there were 32 (37%) and 54 (67%) metastatic and non-metastatic lymph nodes, respectively. The mean values of D, D*, and F(p) did not differ significantly between metastatic and non-metastatic lymph nodes. CONCLUSIONS: IVIM parameters are not useful for differentiation between metastatic and non-metastatic head and neck lymph nodes.

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