Synthesis of Highly Substituted Imidazole Uracil Containing Molecules via Ugi-4CR and Passerini-3CR

[Image: see text] The synthesis of uracil/thymine containing tetra/trisubstituted imidazole derivatives was demonstrated using Ugi/Passerini-reaction followed by a postcyclization reaction sequence. The approach enables the one-pot facile construction of diverse compounds in moderate to excellent yi...

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Detalles Bibliográficos
Autores principales: Madhavachary, Rudrakshula, Zarganes-Tzitzikas, Tryfon, Patil, Pravin, Kurpiewska, Katarzyna, Kalinowska-Tłuścik, Justyna, Dömling, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894062/
https://www.ncbi.nlm.nih.gov/pubmed/29457887
http://dx.doi.org/10.1021/acscombsci.7b00145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894062/
https://www.ncbi.nlm.nih.gov/pubmed/29457887
http://dx.doi.org/10.1021/acscombsci.7b00145

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