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Dysregulated heme oxygenase-1(low) M2-like macrophages augment lupus nephritis via Bach1 induced by type I interferons
BACKGROUND: Innate immunity including macrophages (Mϕ) in lupus nephritis (LN) has been gaining attention, but roles of Mϕ in LN remain uncertain. METHODS: Immunohistochemical staining was performed to determine CD68, CD163, heme oxygenase (HO)-1 (a stress-inducible heme-degrading enzyme with anti-i...
Autores principales: | Kishimoto, Daiga, Kirino, Yohei, Tamura, Maasa, Takeno, Mitsuhiro, Kunishita, Yosuke, Takase-Minegishi, Kaoru, Nakano, Hiroto, Kato, Ikuma, Nagahama, Kiyotaka, Yoshimi, Ryusuke, Igarashi, Kazuhiko, Aoki, Ichiro, Nakajima, Hideaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894134/ https://www.ncbi.nlm.nih.gov/pubmed/29636091 http://dx.doi.org/10.1186/s13075-018-1568-1 |
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