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Metformin restores electrophysiology of small conductance calcium-activated potassium channels in the atrium of GK diabetic rats
BACKGROUND: Small conductance calcium-activated potassium channels (SK channels) play a critical role in action potential repolarization in cardiomyocytes. Recently, the potential anti-arrhythmic effect of metformin in diabetic patients has been recognized, yet the underlying mechanism remains elusi...
Autores principales: | Fu, Xi, Pan, Yilong, Cao, Qian, Li, Bin, Wang, Shuo, Du, Hongjiao, Duan, Na, Li, Xiaodong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894224/ https://www.ncbi.nlm.nih.gov/pubmed/29636010 http://dx.doi.org/10.1186/s12872-018-0805-5 |
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