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New World feline APOBEC3 potently controls inter-genus lentiviral transmission

BACKGROUND: The apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3; A3) gene family appears only in mammalian genomes. Some A3 proteins can be incorporated into progeny virions and inhibit lentiviral replication. In turn, the lentiviral viral infectivity factor (Vif) countera...

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Detalles Bibliográficos
Autores principales: Konno, Yoriyuki, Nagaoka, Shumpei, Kimura, Izumi, Yamamoto, Keisuke, Kagawa, Yumiko, Kumata, Ryuichi, Aso, Hirofumi, Ueda, Mahoko Takahashi, Nakagawa, So, Kobayashi, Tomoko, Koyanagi, Yoshio, Sato, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894237/
https://www.ncbi.nlm.nih.gov/pubmed/29636069
http://dx.doi.org/10.1186/s12977-018-0414-5