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Magnetic resonance imaging findings in diagnosis and prognosis of Wilson disease

Wilson disease (WD) is a rare autosomal recessive disorder characterized by excessive copper deposition in the body, principally in the liver and the brain. There is a wide spectrum of clinical presentations, but the most significant and basic symptoms of the disease can be divided into hepatic, neu...

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Autores principales: Salari, Mehri, Fayyazi, Emad, Mirmosayyeb, Omid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894273/
https://www.ncbi.nlm.nih.gov/pubmed/29692820
http://dx.doi.org/10.4103/jrms.JRMS_362_16
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author Salari, Mehri
Fayyazi, Emad
Mirmosayyeb, Omid
author_facet Salari, Mehri
Fayyazi, Emad
Mirmosayyeb, Omid
author_sort Salari, Mehri
collection PubMed
description Wilson disease (WD) is a rare autosomal recessive disorder characterized by excessive copper deposition in the body, principally in the liver and the brain. There is a wide spectrum of clinical presentations, but the most significant and basic symptoms of the disease can be divided into hepatic, neurologic, and psychiatric manifestations. Magnetic resonance imaging (MRI) provides more detailed anatomical information than computed tomography of the brain, especially of the structure of the basal ganglia and brain stem. In this review, we want to evaluate the correlation between MRI findings and clinical features of WD.
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spelling pubmed-58942732018-04-24 Magnetic resonance imaging findings in diagnosis and prognosis of Wilson disease Salari, Mehri Fayyazi, Emad Mirmosayyeb, Omid J Res Med Sci Review Article Wilson disease (WD) is a rare autosomal recessive disorder characterized by excessive copper deposition in the body, principally in the liver and the brain. There is a wide spectrum of clinical presentations, but the most significant and basic symptoms of the disease can be divided into hepatic, neurologic, and psychiatric manifestations. Magnetic resonance imaging (MRI) provides more detailed anatomical information than computed tomography of the brain, especially of the structure of the basal ganglia and brain stem. In this review, we want to evaluate the correlation between MRI findings and clinical features of WD. Medknow Publications & Media Pvt Ltd 2018-03-27 /pmc/articles/PMC5894273/ /pubmed/29692820 http://dx.doi.org/10.4103/jrms.JRMS_362_16 Text en Copyright: © 2018 Journal of Research in Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Review Article
Salari, Mehri
Fayyazi, Emad
Mirmosayyeb, Omid
Magnetic resonance imaging findings in diagnosis and prognosis of Wilson disease
title Magnetic resonance imaging findings in diagnosis and prognosis of Wilson disease
title_full Magnetic resonance imaging findings in diagnosis and prognosis of Wilson disease
title_fullStr Magnetic resonance imaging findings in diagnosis and prognosis of Wilson disease
title_full_unstemmed Magnetic resonance imaging findings in diagnosis and prognosis of Wilson disease
title_short Magnetic resonance imaging findings in diagnosis and prognosis of Wilson disease
title_sort magnetic resonance imaging findings in diagnosis and prognosis of wilson disease
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894273/
https://www.ncbi.nlm.nih.gov/pubmed/29692820
http://dx.doi.org/10.4103/jrms.JRMS_362_16
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