Characterisation of Newly Emerged Isolates of Classical Swine Fever Virus in China, 2014–2015

INTRODUCTION: In 2014–2015, the epidemic of classical swine fever (CSF) occurred in many large-scale pig farms in different provinces of China, and a subgenotype 2.1d of CSF virus (CSFV) was newly identified. MATERIAL AND METHODS: The phylogenetic relationship, genetic diversity, and epidemic status...

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Detalles Bibliográficos
Autores principales: Leng, Chaoliang, Zhang, Hongliang, Kan, Yunchao, Yao, Lunguang, Li, Mingliang, Zhai, Hongyue, Li, Zhen, Liu, Chunxiao, Shi, Hongfei, Ji, Jun, Qiu, Reng, Tian, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter open 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894411/
https://www.ncbi.nlm.nih.gov/pubmed/29978049
http://dx.doi.org/10.1515/jvetres-2017-0001
Descripción
Sumario:INTRODUCTION: In 2014–2015, the epidemic of classical swine fever (CSF) occurred in many large-scale pig farms in different provinces of China, and a subgenotype 2.1d of CSF virus (CSFV) was newly identified. MATERIAL AND METHODS: The phylogenetic relationship, genetic diversity, and epidemic status of the 2014–2015 CSFV isolates, 18 new CSFV isolates collected in 2015, and 43 other strains isolated in 2014–2015 were fully analysed, together with 163 CSFV reference isolates. RESULTS: Fifty-two 2014–2015 isolates belonged to subgenotype 2.1d and nine other isolates belonged to subgenotype 2.1b. The two subgenotype isolates showed unique molecular characteristics. Furthermore, the 2.1d isolates were found to possibly diverge from 2.1b isolates. CONCLUSION: This study suggests that the Chinese CSFVs will remain pandemic.

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