Von Economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa

Postencephalitic parkinsonism (PEP) is currently perceived as having a very close etiologic relationship with encephalitis lethargica (von Economo’s disease [EL]), with PEP developing immediately after the acute phase of EL or at some time later. EL was classically described by von Economo and has s...

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Autores principales: Bigman, Daniel Y, Bobrin, Bradford D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894716/
https://www.ncbi.nlm.nih.gov/pubmed/29670352
http://dx.doi.org/10.2147/NDT.S153313
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author Bigman, Daniel Y
Bobrin, Bradford D
author_facet Bigman, Daniel Y
Bobrin, Bradford D
author_sort Bigman, Daniel Y
collection PubMed
description Postencephalitic parkinsonism (PEP) is currently perceived as having a very close etiologic relationship with encephalitis lethargica (von Economo’s disease [EL]), with PEP developing immediately after the acute phase of EL or at some time later. EL was classically described by von Economo and has somnolent-ophthalmoplegic, hyperkinetic, and amyostatic-akinetic forms. Previous cases have reported success with levodopa in PEP. We report a case with PEP showing success after administration of levodopa and carbidopa. This case would support the hypothesis that this syndrome effects dopamine neurotransmission.
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spelling pubmed-58947162018-04-18 Von Economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa Bigman, Daniel Y Bobrin, Bradford D Neuropsychiatr Dis Treat Case Report Postencephalitic parkinsonism (PEP) is currently perceived as having a very close etiologic relationship with encephalitis lethargica (von Economo’s disease [EL]), with PEP developing immediately after the acute phase of EL or at some time later. EL was classically described by von Economo and has somnolent-ophthalmoplegic, hyperkinetic, and amyostatic-akinetic forms. Previous cases have reported success with levodopa in PEP. We report a case with PEP showing success after administration of levodopa and carbidopa. This case would support the hypothesis that this syndrome effects dopamine neurotransmission. Dove Medical Press 2018-04-04 /pmc/articles/PMC5894716/ /pubmed/29670352 http://dx.doi.org/10.2147/NDT.S153313 Text en © 2018 Bigman and Bobrin. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Case Report
Bigman, Daniel Y
Bobrin, Bradford D
Von Economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa
title Von Economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa
title_full Von Economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa
title_fullStr Von Economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa
title_full_unstemmed Von Economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa
title_short Von Economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa
title_sort von economo’s disease and postencephalitic parkinsonism responsive to carbidopa and levodopa
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894716/
https://www.ncbi.nlm.nih.gov/pubmed/29670352
http://dx.doi.org/10.2147/NDT.S153313
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