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High-speed optical coherence tomography by circular interferometric ranging
Existing three-dimensional optical imaging methods excel in controlled environments but are difficult to deploy over large, irregular and dynamic fields. This has limited imaging in areas such as material inspection and medicine. To better address these applications, we developed methods in optical...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894866/ https://www.ncbi.nlm.nih.gov/pubmed/29657576 http://dx.doi.org/10.1038/s41566-017-0088-x |
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author | Siddiqui, Meena Nam, Ahhyun S. Tozburun, Serhat Lippok, Norman Blatter, Cedric Vakoc, Benjamin J. |
author_facet | Siddiqui, Meena Nam, Ahhyun S. Tozburun, Serhat Lippok, Norman Blatter, Cedric Vakoc, Benjamin J. |
author_sort | Siddiqui, Meena |
collection | PubMed |
description | Existing three-dimensional optical imaging methods excel in controlled environments but are difficult to deploy over large, irregular and dynamic fields. This has limited imaging in areas such as material inspection and medicine. To better address these applications, we developed methods in optical coherence tomography (OCT) to efficiently interrogate sparse scattering fields, i.e., those in which most locations (voxels) do not generate meaningful signal. Frequency comb sources are used to superimpose reflected signals from equispaced locations through optical subsampling. This results in circular ranging, and reduces the number of measurements required to interrogate large volumetric fields. As a result, signal acquisition barriers that have limited speed and field in OCT are avoided. With a new ultrafast, time-stretched frequency comb laser design operating with 7.6 MHz to 18.9 MHz repetition rates, we achieved imaging of multi-cm(3) fields at up to 7.5 volumes per second. |
format | Online Article Text |
id | pubmed-5894866 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
record_format | MEDLINE/PubMed |
spelling | pubmed-58948662018-07-29 High-speed optical coherence tomography by circular interferometric ranging Siddiqui, Meena Nam, Ahhyun S. Tozburun, Serhat Lippok, Norman Blatter, Cedric Vakoc, Benjamin J. Nat Photonics Article Existing three-dimensional optical imaging methods excel in controlled environments but are difficult to deploy over large, irregular and dynamic fields. This has limited imaging in areas such as material inspection and medicine. To better address these applications, we developed methods in optical coherence tomography (OCT) to efficiently interrogate sparse scattering fields, i.e., those in which most locations (voxels) do not generate meaningful signal. Frequency comb sources are used to superimpose reflected signals from equispaced locations through optical subsampling. This results in circular ranging, and reduces the number of measurements required to interrogate large volumetric fields. As a result, signal acquisition barriers that have limited speed and field in OCT are avoided. With a new ultrafast, time-stretched frequency comb laser design operating with 7.6 MHz to 18.9 MHz repetition rates, we achieved imaging of multi-cm(3) fields at up to 7.5 volumes per second. 2018-01-29 2018 /pmc/articles/PMC5894866/ /pubmed/29657576 http://dx.doi.org/10.1038/s41566-017-0088-x Text en Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms |
spellingShingle | Article Siddiqui, Meena Nam, Ahhyun S. Tozburun, Serhat Lippok, Norman Blatter, Cedric Vakoc, Benjamin J. High-speed optical coherence tomography by circular interferometric ranging |
title | High-speed optical coherence tomography by circular interferometric ranging |
title_full | High-speed optical coherence tomography by circular interferometric ranging |
title_fullStr | High-speed optical coherence tomography by circular interferometric ranging |
title_full_unstemmed | High-speed optical coherence tomography by circular interferometric ranging |
title_short | High-speed optical coherence tomography by circular interferometric ranging |
title_sort | high-speed optical coherence tomography by circular interferometric ranging |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894866/ https://www.ncbi.nlm.nih.gov/pubmed/29657576 http://dx.doi.org/10.1038/s41566-017-0088-x |
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