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High-speed optical coherence tomography by circular interferometric ranging

Existing three-dimensional optical imaging methods excel in controlled environments but are difficult to deploy over large, irregular and dynamic fields. This has limited imaging in areas such as material inspection and medicine. To better address these applications, we developed methods in optical...

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Detalles Bibliográficos
Autores principales: Siddiqui, Meena, Nam, Ahhyun S., Tozburun, Serhat, Lippok, Norman, Blatter, Cedric, Vakoc, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894866/
https://www.ncbi.nlm.nih.gov/pubmed/29657576
http://dx.doi.org/10.1038/s41566-017-0088-x
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author Siddiqui, Meena
Nam, Ahhyun S.
Tozburun, Serhat
Lippok, Norman
Blatter, Cedric
Vakoc, Benjamin J.
author_facet Siddiqui, Meena
Nam, Ahhyun S.
Tozburun, Serhat
Lippok, Norman
Blatter, Cedric
Vakoc, Benjamin J.
author_sort Siddiqui, Meena
collection PubMed
description Existing three-dimensional optical imaging methods excel in controlled environments but are difficult to deploy over large, irregular and dynamic fields. This has limited imaging in areas such as material inspection and medicine. To better address these applications, we developed methods in optical coherence tomography (OCT) to efficiently interrogate sparse scattering fields, i.e., those in which most locations (voxels) do not generate meaningful signal. Frequency comb sources are used to superimpose reflected signals from equispaced locations through optical subsampling. This results in circular ranging, and reduces the number of measurements required to interrogate large volumetric fields. As a result, signal acquisition barriers that have limited speed and field in OCT are avoided. With a new ultrafast, time-stretched frequency comb laser design operating with 7.6 MHz to 18.9 MHz repetition rates, we achieved imaging of multi-cm(3) fields at up to 7.5 volumes per second.
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spelling pubmed-58948662018-07-29 High-speed optical coherence tomography by circular interferometric ranging Siddiqui, Meena Nam, Ahhyun S. Tozburun, Serhat Lippok, Norman Blatter, Cedric Vakoc, Benjamin J. Nat Photonics Article Existing three-dimensional optical imaging methods excel in controlled environments but are difficult to deploy over large, irregular and dynamic fields. This has limited imaging in areas such as material inspection and medicine. To better address these applications, we developed methods in optical coherence tomography (OCT) to efficiently interrogate sparse scattering fields, i.e., those in which most locations (voxels) do not generate meaningful signal. Frequency comb sources are used to superimpose reflected signals from equispaced locations through optical subsampling. This results in circular ranging, and reduces the number of measurements required to interrogate large volumetric fields. As a result, signal acquisition barriers that have limited speed and field in OCT are avoided. With a new ultrafast, time-stretched frequency comb laser design operating with 7.6 MHz to 18.9 MHz repetition rates, we achieved imaging of multi-cm(3) fields at up to 7.5 volumes per second. 2018-01-29 2018 /pmc/articles/PMC5894866/ /pubmed/29657576 http://dx.doi.org/10.1038/s41566-017-0088-x Text en Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Siddiqui, Meena
Nam, Ahhyun S.
Tozburun, Serhat
Lippok, Norman
Blatter, Cedric
Vakoc, Benjamin J.
High-speed optical coherence tomography by circular interferometric ranging
title High-speed optical coherence tomography by circular interferometric ranging
title_full High-speed optical coherence tomography by circular interferometric ranging
title_fullStr High-speed optical coherence tomography by circular interferometric ranging
title_full_unstemmed High-speed optical coherence tomography by circular interferometric ranging
title_short High-speed optical coherence tomography by circular interferometric ranging
title_sort high-speed optical coherence tomography by circular interferometric ranging
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894866/
https://www.ncbi.nlm.nih.gov/pubmed/29657576
http://dx.doi.org/10.1038/s41566-017-0088-x
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