Germline mutations in candidate predisposition genes in individuals with cutaneous melanoma and at least two independent additional primary cancers

BACKGROUND: While a number of autosomal dominant and autosomal recessive cancer syndromes have an associated spectrum of cancers, the prevalence and variety of cancer predisposition mutations in patients with multiple primary cancers have not been extensively investigated. An understanding of the va...

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Detalles Bibliográficos
Autores principales: Pritchard, Antonia L., Johansson, Peter A., Nathan, Vaishnavi, Howlie, Madeleine, Symmons, Judith, Palmer, Jane M., Hayward, Nicholas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894988/
https://www.ncbi.nlm.nih.gov/pubmed/29641532
http://dx.doi.org/10.1371/journal.pone.0194098

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