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Memory deficiency, cerebral amyloid angiopathy, and amyloid-β plaques in APP+PS1 double transgenic rat model of Alzheimer’s disease

Transgenic rat models of Alzheimer’s disease were used to examine differences in memory and brain histology. Double transgenic female rats (APP+PS1) over-expressing human amyloid precursor protein (APP) and presenilin 1 (PS1) and single transgenic rats (APP21) over-expressing human APP were compared...

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Detalles Bibliográficos
Autores principales:	Klakotskaia, Diana, Agca, Cansu, Richardson, Rachel A., Stopa, Edward G., Schachtman, Todd R., Agca, Yuksel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895023/ https://www.ncbi.nlm.nih.gov/pubmed/29641600 http://dx.doi.org/10.1371/journal.pone.0195469

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