Structural and functional analysis of Utp24, an endonuclease for processing 18S ribosomal RNA

The precursor ribosomal RNA is processed by multiple steps of nucleolytic cleavage to generate mature rRNAs. Utp24 is a PIN domain endonuclease in the early 90S precursor of small ribosomal subunit and is proposed to cleave at sites A1 and A2 of pre-rRNA. Here we determine the crystal structure of U...

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Detalles Bibliográficos
Autores principales: An, Weidong, Du, Yifei, Ye, Keqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895043/
https://www.ncbi.nlm.nih.gov/pubmed/29641590
http://dx.doi.org/10.1371/journal.pone.0195723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895043/
https://www.ncbi.nlm.nih.gov/pubmed/29641590
http://dx.doi.org/10.1371/journal.pone.0195723

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