Statin in the treatment of patients with myocardial infarction: A meta-analysis

The purpose of this meta-analysis is to investigate whether statin is a key therapy for myocardial infarction (MI) by comparing all randomized controlled trials that appraised the effects of statin on risk of MI. Pubmed, Embase, and Medline databases (up to December 2016) were used to search all rel...

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Detalles Bibliográficos
Autores principales: Han, Xue, Zhang, Yi, Yin, Lin, Zhang, Lin, Wang, Yue, Zhang, Hongshan, Li, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
4200
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895306/
https://www.ncbi.nlm.nih.gov/pubmed/29561426
http://dx.doi.org/10.1097/MD.0000000000010167
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author Han, Xue
Zhang, Yi
Yin, Lin
Zhang, Lin
Wang, Yue
Zhang, Hongshan
Li, Bo
author_facet Han, Xue
Zhang, Yi
Yin, Lin
Zhang, Lin
Wang, Yue
Zhang, Hongshan
Li, Bo
author_sort Han, Xue
collection PubMed
description The purpose of this meta-analysis is to investigate whether statin is a key therapy for myocardial infarction (MI) by comparing all randomized controlled trials that appraised the effects of statin on risk of MI. Pubmed, Embase, and Medline databases (up to December 2016) were used to search all related articles. Using the data from 18 available publications, we examined the efficacy in treating or reducing the risk of MI by using random-effects models of odds ratio (OR) comparing the highest with the lowest category. Statins have demonstrated efficacy in treating or reducing the risk of MI (OR = 0.73, 95% confidence interval = 0.58–0.93, P = .010). This meta-analysis suggests that statin have light efficacy in treating or reducing the risk of MI patients.
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spelling pubmed-58953062018-04-18 Statin in the treatment of patients with myocardial infarction: A meta-analysis Han, Xue Zhang, Yi Yin, Lin Zhang, Lin Wang, Yue Zhang, Hongshan Li, Bo Medicine (Baltimore) 4200 The purpose of this meta-analysis is to investigate whether statin is a key therapy for myocardial infarction (MI) by comparing all randomized controlled trials that appraised the effects of statin on risk of MI. Pubmed, Embase, and Medline databases (up to December 2016) were used to search all related articles. Using the data from 18 available publications, we examined the efficacy in treating or reducing the risk of MI by using random-effects models of odds ratio (OR) comparing the highest with the lowest category. Statins have demonstrated efficacy in treating or reducing the risk of MI (OR = 0.73, 95% confidence interval = 0.58–0.93, P = .010). This meta-analysis suggests that statin have light efficacy in treating or reducing the risk of MI patients. Wolters Kluwer Health 2018-03-23 /pmc/articles/PMC5895306/ /pubmed/29561426 http://dx.doi.org/10.1097/MD.0000000000010167 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-sa/4.0 This is an open access article distributed under the Creative Commons Attribution-ShareAlike License 4.0, which allows others to remix, tweak, and build upon the work, even for commercial purposes, as long as the author is credited and the new creations are licensed under the identical terms. http://creativecommons.org/licenses/by-sa/4.0
spellingShingle 4200
Han, Xue
Zhang, Yi
Yin, Lin
Zhang, Lin
Wang, Yue
Zhang, Hongshan
Li, Bo
Statin in the treatment of patients with myocardial infarction: A meta-analysis
title Statin in the treatment of patients with myocardial infarction: A meta-analysis
title_full Statin in the treatment of patients with myocardial infarction: A meta-analysis
title_fullStr Statin in the treatment of patients with myocardial infarction: A meta-analysis
title_full_unstemmed Statin in the treatment of patients with myocardial infarction: A meta-analysis
title_short Statin in the treatment of patients with myocardial infarction: A meta-analysis
title_sort statin in the treatment of patients with myocardial infarction: a meta-analysis
topic 4200
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895306/
https://www.ncbi.nlm.nih.gov/pubmed/29561426
http://dx.doi.org/10.1097/MD.0000000000010167
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